Endocrine Abstracts

An 85 year old lady was admitted with painless jaundice and cholestatic liver functions (LFTs). Investigations organised by gastroenterologists were fine including hepatitis viral screen, copper and ceruloplasmin levels, alpha -one antitrypsin, alpha -fetoprotein, immunoglobulins, auto-immune screen and ultrasound scan of the liver. In view of palpitations and weight loss, thyroid functions (TFTs) were done and showed biochemical hyperthyroidism: FT4 of 36.8 pmol/L (12–22...

Introduction: Amiodarone is a class III antiarrhythmic agent widely used in the treatment of atrial and ventricular arrhythmias.Amiodarone is known to cause thyroid dysfunction in three ways; amiodarone induced hypothyroidism, amiodarone induced thyrotoxicosis (AIT) type I and type II.We present a case of a patient with AIT type II who subsequently developed hypothyroidism.Case presentation: A 43-year-old man...

A 48-year-old gentleman was referred to the endocrine team with abnormal thyroid function tests (TFTs). His background history included cardiomyopathy complicated by atrial fibrillation (AF). He had been treated with amiodarone for a year. TFTs were monitored regularly during treatment and were normal. Four months after stopping amiodarone, he complained of weight loss, sweating and tremor. He had no family history of thyroid disease. He had a resting heart rate of 120/min (AF...

Background: Hyperinsulinemic hypoglycaemia (HH) after Roux-en-Y gastric bypass (RYGB) is rare. Patients typically present with post-prandial hypoglycaemia >1 year after surgery and once weight loss has plateaued. Despite multiple treatment options, the management of these patients remains challenging.Clinical case: A 31-year-old female was referred for bariatric surgery with a BMI of 41.4 kg/m2. In the year preceding the r...